Sunday, March 3, 2013

Le petit juriste | How to best combat spam?

Introduction

The problematic of unsolicited bulk email, commonly referred to as ?spam? is, an ever-increasing worrying and probably one of the largest issue on the Internet. Nowadays, does the email spam still concern a lot of people considering that newest generations communicate with instant messaging system, through Facebook or Tweeter, via their iPhone? According to the Coalition Against Unsolicited Commercial Email, the answer is yes and the conclusions of a recent study confirm that email is still the top online activity, all generations considered. Furthermore; a recent Nielsen study shows that the first activity on mobiles devices is emailing and not social networking. One step further, in a Radicati Group report, the number of email users is forecasted to attain 1.9 billion by 2013. Because email has still significance, the spammers still value this communication tool.It is therefore crucial to find ways which permit to battle this security and privacy threat. In March 2011, spams represented 79.6 % of the emails traffic in the USA, against 79.1 % for the UK and 80.2 % in the Netherlands. Clearly, spam exceeded the stage of simple online annoyance. In spite of technological advancements, it is expected by 2014 that 19 % of email transferred to users? mailboxes will nevertheless be spam.

Although the definition of spam can be broad and that spam can encompass numerous sorts of messages, the present work will mainly focus on ?unsolicited commercial email?. Spam must be battle on all fronts. This is why, from a manifold perspective, the present work will argue what are the optimal ways to defeat spam.

USA?s legislation, global definition, social networks

  1. Legal perspective

As many lawyers would agree, the legislative framework is probably not the best manner to cure spam. Indeed, the ?legislation is a blunt instrument with which to beat junk email?.1

Worldwide, lots of anti-spam legislations have been designed. Even worst, the CAN-SPAM Act (CPA) has the criticized opposite effect of making spam legal instead of prohibiting it. Nonetheless, one interesting clause, highly supported by Lessig, considers the establishment of a report mechanism. Individuals who help chasing breaches of the Act become entitled to perceive a reward. However, Tompkins and Handley argue that such a system would cause people breaching laws and could be an encouragement for hackers to violate people?s privacy.

The USA?s legislation is very weak, too superficial according to Mozena. It is totally antagonist to the EU one, as well as to the legislation in Australia and China, where spamming is not legal. Besides laws, it is thought that self-regulation system is not the adequate solution to circumvent spam, where it seems now clear that it cannot play an important role anymore and should be substituted by binding laws in order to prevent marketer?s? abusive practices.

The main shortcomings of the regulations may be mainly explained as follow. Firstly, there is no global definition of what constitutes a spam. According to Starr, the central elements to define spam, i.e. unsolicited, bulk and commercial, are not adaptable to fit in a global spam explanation. Furthermore, Van Alstyne stresses that ?recipients themselves do not agree on what constitutes spam?.2

Secondly, the law is restricted to a single jurisdiction. Indeed, EU laws are only applicable within the Union and the vast majority of spams emanates from outwith, which inevitably leads to a chaotic enforcement of anti-spam regulations. Indeed, about 90 % of EU spam troubles come from the USA where spamming is legal. Meanwhile, cybercriminals do not have boundaries and may even remote spamming, through a network of ?zombie? computers.

Noteworthy, even if sender and recipient of email spam are both living in the same country or state, it does not automatically implies that the domestic law will apply, as it is very plausible that the email was dispatched via a server situated elsewhere.

Nevertheless, it is reasonable to argue that the Canadian Anti-Spam legislation (Bill C-28) will constitute an effective law, taking the best from the EU 2009 Directive and the USA Act. Embodying an opt-in regime, the bill provides for drastic penalties applicable to spammers. However, online, the identity of spammers is not easily detectable and fake identities can be used. Interestingly, the bulk character of the email spam would be irrelevant as the law would apply as soon as a single email is forwarded.

In conclusion, Starr is right when saying that ?at best, anti-spam laws are ineffective; at worst, they cause more problems than spam itself?.3 Only when a regulation of global significance will be designed or when worldwide laws will be consistent, the law will stop constituting a utopic instrument to eradicate spam. Additionally, such law(s) would need to call for transborder enforcement, key feature the international scene is currently lacking of. Besides, cross-border prosecution can be arduous where 88.2 % of all spam is sent from botnets of ?zombie computers?, where identity of the real sender is hidden. So, the spam issue encompasses more than just some loopholes in the global legislative framework(s). The willing to find a global consensus will always face two issues: either adopting a consumer-oriented law generally characterised by an opt-in system, such as the EU and Canadian laws, or a business-focused law generally characterised by an opt-out regime, such as the CPA. Basically, balancing interests are at stake. Undertakings need to be allowed to freely send advertisement emails but consumer?s privacy and consent should be preserved. Ultimately, it is wise to mention that ?criminalization requires a clear definition of the crime and an ability to catch the criminal. Neither is possible with spam?.

  1. Technological perspective

To solve the spam problem, why not just stop using emails, mobile phones, the Internet? Let?s face it; nobody wants to go back in time. Yet, according to a 2003 study, more and more people are tempted to partly or completely give up the use of email because of spam.

The elementary step to curb spam is the use of a content-base or Bayesian filter by the Internet Service Providers (ISPs) and the end-users. This allows solving the issue respectively uphill and downhill. However, spam filters are not foolproof and legitimate emails may seem for the filters to be unsolicited and sometimes may still be returned to the expedient without the receiver having knowledge of them. The main drawback of filters is highlighted by Loder et al: the ?language plasticity permits an escalating arms race in which one side seeks better ways to block unwanted access and the other seeks better ways to gain it?.4 Yet, the Guardian stated in 2004 that dispatching unsolicited email was more difficult nowadays, where spammer must ?play dirty? in order to fool filters.

Just to mention it, the black and whitelists registries system are usually not effective as spammer can buy inexpensive new identities or forge others? identities (spoofing). Interestingly, a September 2011 study empirically reveals that a Support Vector Machine, developed to distinguish end-user and legitimate mail servers machines, greatly surpasses current largely employed blacklists, where filtering accuracy is drastically improved.

3.1. Spamgourmet

One valuable manner to eliminate spam is to utilise a free of charge discardable email address instead of one?s real email address. This is the method employed by Spamgourmet. It is thought this website provides for an effective solution to avoid spams. This was even advocated at the ABA TECHSHOW 2011. It offers disposable and time limited email addresses through a very simple functioning. A temporary address is created to receive a number of messages predefined by the user, and once the quota is exceeded, messages sent to that address will be automatically deleted. In practice, the user needs to register on spamgourmet.com. It will be asked to provide a username and a valid email address (protected address) where an activation link will be sent. Then, Spamgourmet will transmit the messages dispatched to the user?s disposable addresses to the protected address. After registration, the user disposes of the discardable addresses which will self-destroy after a period of time. Those addresses will always have the same format:

oneword.x.your_username@spamgourmet.com

?Oneword? stands for a simple word allowing the user to remember where a given address was used. ?X? reveals the number of times (maximum 20) Spamgourmet may receive emails using this address before it destroys them. ?Username? is self-explaining. The advantage of Spamgourmet is that the user does not have to come back on the website to create a disposable address before being able to actually using it, as opposed to other websites supplying the same service.

3.2. Camouflage of an email address

If a user prefers to conserve its ?real? email address, more relatively sophisticated ways exists in order to dissimulate an address from spam robots. For instance, the ?@? symbol may easily be replaced by the term ?at? or a hexadecimal code; image containing an email address can be used instead of plain text too. It is thought that the latter, functioning on the same principle as the (Re)Captcha, is the most secured solution from a layman perspective. An alternative manner, but requiring a more in-depth knowledge of the internet, is to utilise a JavaScript.

One current trend of spammer is to use social networks such as Facebook and Twitter or fora. Indeed, every user of these networks is an easy spam target as spam robots continually scan these platforms to gather emails. Therefore, an effective way to receive less spam could be to use the Scr.im website solution. It protects an email address against spam, making it accessible through a safe and short personalised URL address. Concretely, instead of giving an address under its traditional format such as ?xxx@hotmail.com?, the user provides a personalised web link obtained thanks to Scrim into the following format: http://scr.im/1?2. Subsequently, everyone wishing to send an email to a ?Scrim? address?s user has to enter the proposed URL which will unmask, after a basic test spam devices are not able to cross, the user actual address. Eventually, this free device retains the address imperceptible and blocks spam.

To conclude, contrary to the law, technology has no boundaries. According to Grimes, the ?the final solution that seems to have the best chance according to most experts is a technological solution?.5

  1. Economical perspective

According to Van Alstyne, ?the two most common? perspectives referred above did (and will) have only a limited success. A step further, McCullaghn affirms that ?spam is not primarily a technological or legal problem: it?s an economic one?.6 Indeed, as long as there will remain a mutual interest both for spammers and anti-spammers for the spams to survive, no concrete answer to spam can be framed. On one hand, spammers? aim is attracting people with their advertisements. On the other a proportion of their opponents seem to be relatively happy with that. In fact, it is thought that undertakings vendors of anti-spam equipment have a genuine economic interest that spam keeps spreading on the Net. For instance, according to a Radicati Group study, the foreseen email security market share, where anti-spam products represents an important segment, will grow to attain in 2014 more than 7 billion US dollars, which is far superior than what the spammers will earn.

Spam is a parasite advertisement in the sense that it switches the costs of the operation on the targets? shoulders, costing IPSs and the Internet users? resources and time. Indeed, sending a single or bulk email(s) is cheap and therefore the low costs engaged can easily be recovered even if only a portion of emails provides economic results. Until the end of this scheme, spammers will evermore have a pecuniary interest into spamming, as only a few purchases is necessary for spam to be a lucrative activity.

Therefore, why a sort of payment system is not in place? In an experimental survey, where an example of a market mechanism is used to deploy human attention, it was held that by imposing postage fees for emails, senders will be more selective and smaller quantities of message will be sent. Although the authors acknowledge that this solution has potential they also point out that it still needs to be fully attained. Indeed, its first challenge is the tough task to change people?s minds on the way to charge for something which has been free from decades. The second is devising the adequate manner of the pricing mechanism. But the major counter-argument to impose such a payment system, which will arguably prevail for a long time, is that it would represent a huge ?technological step backward? as well as express a ?tacit admission of defeat? to the spam threat, regardless of the smallness of the payment. Nonetheless, it is thought that Kraut et al are right when arguing about the pricing mechanism that ?given sufficient societal benefits, the shift is possible? as it was the case when people shifted from ?free broadcast TV to fee-based cable and pay per view TV?.

Another instrument to allocate human attention is the ?selling interrupt rights? mechanism devised by Fahlman and explored in a more superficial way in Ayres and Nalebuff book. Based on the same pricing email idea, this mechanism provides for that when a sender wishes to interact with someone via emails, he must pay a fee for disturbing this potential customer. When the recipient is willing to contract or not, he will either drop the fee or solicit it. Similarly as the above pricing system, sender?s emails would therefore be very targeted. Fahlman?s scheme is thought to be at least as captivating as the aforementioned one, probably even more.

Eventually, it should be clearly kept in mind that sending bulk unsolicited emails is an ill-advised practice not to be used by undertakings, where a ?wealth of information? may bring on a ?poorness of attention?,7 what should contravene the ?freedom of commercial speech? advocates by Weintzen.

  1. Conclusion

?Two years from now, spam will be solved?.8 The famous Gate?s quote in 2004, where he underestimated the spam issue, without taking into account that the anti-spam solution will not be found soon and solely in the technology. In spite of the numerous interesting suggested solutions/initiatives, it is careful to realize that a conclusive way to eradicate spam cannot yet be foreseen.

Implementation of anti-spam laws within diverse jurisdiction and anti-spam alliances shaped by leading IT undertakings have not contributed to a curtailment regarding spam. At most, a multidisciplinary approach should be able to lessen the spam problematic. Indeed, according to Cowper, ?a global problem needs a global solution?.9 Through this work, it has been demonstrated that ?there?s not one single way to eliminate the problem [?] only a combination of initiatives?.10 Therefore any manner to stem spam will encompass a key concept: the international multidisciplinary cooperation.

The present work was limited to three perspectives: legal, technological and economic. Further researches should focus on the social, educational, ethical and environmental perspectives of spam.

Garry Trillet
LL.M. student in European and international Intellectual Property law at CEIPI
University of Strasbourg

Source: http://www.lepetitjuriste.fr/propriete-intellectuelle/how-to-best-combat-spam?utm_source=rss&utm_medium=rss&utm_campaign=how-to-best-combat-spam

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Saturday, March 2, 2013

Tambora Erupts in 1815 and Changes World History [Excerpt]

In 1816 a remarkable thing happened?there was no summer weather in much of the Northern Hemisphere. This excerpt from The Year without Summer explains why


tambora-caldera SUMMER KILLER: The eruption of Mount Tambora was so powerful that it blocked enough sunlight to change global weather. Image: Courtesy of Jialiang Gao

From The Year without Summer, by William K. Klingaman and Nicholas P. Klingaman. Copyright ? 2013, by the authors and reprinted by permission of Saint Martin?s Press, LLC.

JUST BEFORE SUNSET on April 5, 1815, a massive explosion shook the volcanic island of Sumbawa in the Indonesian archipelago. For two hours, a stream of lava erupted from Mount Tambora, the highest peak in the region, sending a plume of ash eighteen miles into the sky.

More than eight hundred miles away, Thomas Stamford Raffles, the lieutenant-governor of Java, heard the blast at his residence and assumed it came from cannon firing in the distance. Other British authorities on the island made the same mistake. Fearing a neighboring village was under attack, the commander of the city of Djogjokarta, in central Java, dispatched troops to repel the invaders. Officials along the coast interpreted the sounds as signals from a ship in distress, and launched rescue boats to look for survivors.

At Makassar on the southwestern tip of Sulawesi, 240 miles northeast of Tambora, the commander of the Benares, a cruiser of the British East India Company, reported ?a firing of cannon? on April 5. The explosions appeared to come from the south; as they continued, ?the reports seemed to approach much nearer, and sounded like heavy guns occasionally, with slighter reports between.? Assuming that pirates were in the area, the Benares put to sea and spent the next three days scouring nearby islands for any signs of trouble, but found nothing. Nearly five hundred miles farther to the east, the British resident on the island of Ternate heard ?several very distinct reports like heavy cannon,? and sent another cruiser, the Teignmouth, to investigate. It, too, returned empty-handed.

British authorities might have been excused for assuming that the threatening sounds came from potential enemies rather than the earth itself. They were not yet accustomed to the frequent volcanic eruptions that plagued the Indonesian islands. Britain had gained control of Java and the surrounding islands less than four years earlier, when British troops overwhelmed a vastly outnumbered band of French defenders who themselves had held Java for only a short time, having taken it from the Dutch when France conquered the Netherlands in 1794. By the spring of 1815, neither the government in London nor the British East India Company was entirely certain that they wanted to keep the island, since the expense of administering and defending it had outweighed the commercial benefits thus far.

Responsibility for British policy on the scene lay squarely with Raffles himself. The son of a ship?s captain, Raffles?who actually was born at sea, off the coast of Jamaica?dreamt of a British maritime empire throughout South Asia, an ?Eastern insular Empire? that would provide new markets for English cotton and woolen textiles, and a profitable supply of coffee and sugar for Europe. It was Raffles who had persuaded the governor general of India, Lord Minto, to seize Java in the first place. Raffles also hoped to use Java as an avenue to improve relations with Japan, which he viewed as a rising Asiatic power. Meanwhile, heeding Minto?s advice to ?do as much good as we can? while governing Java, Raffles reformed the colonial administration of the island, limiting the powers of the great landowners over their tenants and ameliorating the worst abuses of slavery while banning the importation of slaves under fourteen years of age.

But Raffles? interests in the region extended beyond politics and commerce. After years of study, he was sufficiently fluent in the Malay language to conduct discussions directly with local chieftains. He regularly employed botanists and zoologists to obtain?at his own expense?specimens of local flora and wildlife, some of which he had preserved in spirit and shipped back to Britain. In his capacity as president of the Batavian Society, dedicated to the study of Java?s natural history, Raffles frequently toured the island and recorded his observations of geological phenomena. Several weeks before Mount Tambora erupted, Raffles became the first European to ascend a nearby mountain known as Gunong Gede; by using thermometers to measure the difference in temperature between the base and the peak, Raffles and his companions determined that they had climbed at least seven thousand feet. ?We had a most extensive prospect from the summit,? he subsequently wrote to a friend. ?The islands all round were quite distinct and we traced the sea beyond the southernmost point of Sumatra; the surf on the south coast was visible to the naked eye.?

Source: http://rss.sciam.com/click.phdo?i=3c16d97ffe554805e52dbf27e3ca70ff

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Gridlock: No budging at the budget-cuts deadline

President Barack Obama speaks to reporters in the White House briefing room in Washington, Friday, March 1, 2013, following his meeting with congressional leaders regarding the automatic spending cuts. (AP Photo/Pablo Martinez Monsivais)

President Barack Obama speaks to reporters in the White House briefing room in Washington, Friday, March 1, 2013, following his meeting with congressional leaders regarding the automatic spending cuts. (AP Photo/Pablo Martinez Monsivais)

House Speaker John Boehner of Ohio speaks to reporters outside the White House in Washington, Friday, March 1, 2013, following a meeting with President Barack Obama and Congressional leaders regarding the automatic spending cuts. (AP Photo/Carolyn Kaster)

President Barack Obama pause as he speaks to reporters in the White House briefing room in Washington, Friday, March 1, 2013, following a meeting with congressional leaders regarding the automatic spending cuts. (AP Photo/Carolyn Kaster)

House Speaker John Boehner of Ohio arrives on Capitol Hill in Washington, Friday, March 1, 2013, after a meeting at the White House between President Barack Obama and Congressional leaders before billions of dollars in mandatory budget cuts were to start. The meeting ? lasting less than an hour ? yielded no immediate results. (AP Photo/J. Scott Applewhite)

House Speaker John Boehner of Ohio talks to reporters outside the White House in Washington, Friday, March 1, 2013, following a meeting with President Barack Obama and Congressional leaders regarding the automatic spending cuts. (AP Photo/Charles Dharapak)

(AP) ? Gridlocked once more, President Barack Obama and Republican congressional leaders refused to budge in their budget standoff Friday as $85 billion in across-the-board spending cuts bore down on individual Americans and the nation's still-recovering economy. "None of this is necessary," said the president after a sterile White House meeting that portended a long standoff.

Even before Obama formally ordered the cuts required by midnight, their impact was felt thousands of miles away. In Seattle, the King County Housing Authority announced it had stopped issuing housing vouchers under a federal program that benefits "elderly or disabled households, veterans, and families with children."

The president met with top lawmakers for less than an hour at the White House, then sought repeatedly to fix the blame on Republicans for the broad spending reductions and any damage that they inflict. "They've allowed these cuts to happen because they refuse to budge on closing a single wasteful loophole to help reduce the deficit," he said, renewing his demand for a comprehensive deficit-cutting deal that includes higher taxes.

Republicans said they wanted deficit cuts, too, but not tax increases. "The president got his tax hikes on Jan. 1," House Speaker John Boehner told reporters, a reference to a $600 billion increase on higher wage earners that cleared Congress on the first day of the year. Now, he said after the meeting, it is time take on "the spending problem here in Washington."

Senate Republican leader Mitch McConnell of Kentucky was equally emphatic. " I will not be part of any back-room deal, and I will absolutely not agree to increase taxes," he vowed in a written statement.

At the same time they clashed, Obama and Republicans appeared determined to contain their disagreement.

Boehner said the House will pass legislation next week to extend routine funding for government agencies beyond the current March 27 expiration. "I'm hopeful that we won't have to deal with the threat of a government shutdown while we're dealing with the sequester at the same time," he said, referring to the new cuts by their Washington-speak name.

Obama said he, too, wanted to keep the two issues separate.

White House officials declined to say precisely when the president would formally order the cuts. Under the law, he had until midnight. Barring a quick deal in the next week or so to call them off, the impact eventually is likely to be felt in all reaches of the country.

The Pentagon will absorb half of the $85 billion required to be sliced between now and the end of the budget year on Sept 30, exposing civilian workers to furloughs and defense contractors to possible cancellations. Said Defense Secretary Chuck Hagel, only a few days on the job: "We will continue to ensure America's security" despite the challenge posed by an "unnecessary budget crisis."

The administration also has warned of long lines at airports as security personnel are furloughed, of teacher layoffs in some classrooms and adverse impacts on maintenance at the nation's parks.

The announcement by the housing agency in Seattle was an early indication of what is likely to hit as the cuts take effect. It said it was taking the action "to cope with the impending reduction in federal funding," adding that it normally issues 45 to 50 vouchers per month.

After days of dire warnings by administration officials, the president told reporters the effects of the cuts would be felt only gradually.

"The longer these cuts remain in place, the greater the damage to our economy ? a slow grind that will intensify with each passing day," he said. Much of the budget savings will come through unpaid furloughs for government workers, and those won't begin taking effect until next month.

Obama declined to say if he bore any of the responsibility for the coming cuts, and expressed bemusement at any suggestion he had the ability to force Republicans to agree with him.

"I am not a dictator. I'm the president," he said. "So, ultimately, if Mitch McConnell or John Boehner say we need to go to catch a plane, I can't have Secret Service block the doorway, right?" He also declared he couldn't perform a "Jedi mind meld" to sway opponents, mixing Star Wars and Star Trek as he reached for a science fiction metaphor.

Neither the president nor Republicans claimed to like what was about to happen. Obama called the cuts "dumb," and GOP lawmakers have long said they were his idea in the first place.

Ironically, they derive from a budget dispute they were supposed to help resolve back in the fall of 2011. At the time, a congressional Supercommittee was charged with identifying at least $1.2 trillion in deficit savings over a decade as part of an attempt to avoid a first-ever government default. The president and Republicans agreed to create a fallback of that much in across-the-board cuts, designed to be so unpalatable that it would virtually assure the panel struck a deal.

The Supercommittee dissolved in disagreement, though. And while Obama and Republicans agreed to a two-month delay last January, there was no bipartisan negotiation in recent days to prevent the first installment of the cuts from taking effect.

It isn't clear how long they will last.

Of particular concern to lawmakers in both parties is a lack of flexibility in the allocation of cuts due to take effect over the next few months. That problem will ease beginning with the new budget year on Oct. 1, when Congress and the White House will be able to negotiate changes in the way the reductions are made.

For his part, Obama suggested he was content to leave them in place until Republicans change their minds about raising taxes by closing loopholes.

"If Congress comes to its senses a week from now, a month from now, three months from now, then there's a lot of open running room there for us to grow our economy much more quickly and to advance the agenda of the American people dramatically," he said.

"So this is a temporary stop on what I believe is the long-term, outstanding prospect for American growth and greatness."

But Republicans say they are on solid political ground. At a retreat in January in Williamsburg, Va., GOP House members reversed course and decided to approve a debt limit increase without demanding cuts. They also agreed not to provoke a government shutdown, another traditional pressure point, as leverage to force Obama and Democrats to accept savings in benefit programs like Medicare, Medicaid and Social Security.

Obama has said repeatedly he's willing to include benefit programs in deficit-cutting legislation ? as long as more tax revenue is part of the deal.

"I am prepared to do hard things and to push my Democratic friends to do hard things," he said at the White House on Friday.

Republicans speak dismissively of such pledges, saying that in earlier negotiations, the president has never been willing to close a deal with the type of changes he often says he will accept.

___

Associated Press writers Robert Burns, Andrew Taylor, Jim Kuhnhenn and Darlene Superville in Washington and Manuel Valdes in Seattle contributed to this story.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-01-Budget%20Battle/id-853281865abb4e3fb64695f08000895c

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'Rain Man'-like brains mapped at using MRIs and network analysis

Feb. 28, 2013 ? Combining hospital MRIs with the mathematical tool known as network analysis, a group of researchers at UC San Francisco and UC Berkeley have mapped the three-dimensional global connections within the brains of seven adults who have genetic malformations that leave them without the corpus callosum, which connects the left and right sides of the brain.

These "structural connectome" maps, described in the upcoming April 15, 2013 issue of the journal Neuroimage, reveal new details about the condition known as agenesis of the corpus callosum, which is one of the top genetic causes of autism and was part of the mysterious brain physiology of Laurence Kim Peek, the remarkable savant portrayed by Dustin Hoffman in the 1987 movie "Rain Man."

While some people born with agenesis of the corpus callosum are of normal intelligence and do not have any obvious signs of neurologic disease, approximately 40 percent of people with the condition are at high risk for autism. Given this, the work is a step toward finding better ways to image the brains of people with the condition, said Pratik Mukherjee, MD, PhD, a professor of radiology and biomedical imaging at UCSF who was the co-senior author of the research.

Understanding how brain connectivity varies from person to person may help researchers identify imaging biomarkers for autism to help diagnose it and manage care for individuals. Currently autism is diagnosed and assessed based on cognitive tests, such as those involving stacking blocks and looking at pictures on flip cards.

While the new work falls short of a quantitative measure doctors could use instead of cognitive testing, it does offer a proof-of-principle that this novel technique may shed light on neurodevelopment disorders.

"Because you are looking at the whole brain at the network level, you can do new types of analysis to find what's abnormal," Mukherjee said.

The Connection between the Brain Hemispheres and Autism Agenesis of the corpus callosum can arise if individuals are born missing DNA from chromosome 16 and often leads to autism.

Scientists have long puzzled over what the link is between this disorder and the autistic brain, said co-senior author of the paper Elliott Sherr, MD, PhD, professor of neurology and genetics especially since not all people with this malformation develop autism.

Doctors believe this is because the brain has a rich capacity for rewiring in alternative ways.

Pursuing this question, Mukherjee and Sherr turned to MRI and the mathematical technique of network analysis, which has long supported fields like civil engineering, helping urban planners optimize the timing of traffic lights to speed traffic. This is the first time network analysis has been applied to brain mapping for a genetic cause of autism.

The brain offers a significantly complicated challenge for analysis because, unlike the streets of a given city, the brain has hundreds of billions of neurons, many of which make tens of thousands of connections to each other, making its level of connectivity highly complex.

By comparing the seven rain man-like brains to those of 11 people without this malformation, the scientists determined how particular structures called the cingulate bundles were smaller and the neurons within these bundles were less connected to others in the brain. They also found that the network topology of the brain was more variable in people with agenesis of the corpus callosum than in people without the malformation.

The article, "The structural connectome of the human brain in agenesis of the corpus callosum" is authored by Julia P. Owen, a postdoctoral fellow at UCSF, with co-authors Yi-Ou Li, Etay Ziv, Zoe Strominger, Jacquelyn Gold, Polina Bukhpun, Mari Wakahiro, Eric J. Friedman, Elliott H. Sherr and Pratik Mukherjee. It appears in the April 15, 2013 issue of the journal Neuroimage, and is now published online ahead of print.

This work was funded by the National Institutes of Health through grant #R01NS060776, #R01NS060776 and #R01NS058721. Additional support was provided by a grant from the UCSF Sandler Program for Breakthrough Biomedical Research.

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The above story is reprinted from materials provided by University of California, San Francisco (UCSF), via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Julia P. Owen, Yi-Ou Li, Etay Ziv, Zoe Strominger, Jacquelyn Gold, Polina Bukhpun, Mari Wakahiro, Eric J. Friedman, Elliott H. Sherr, Pratik Mukherjee. The structural connectome of the human brain in agenesis of the corpus callosum. NeuroImage, 2013; 70: 340 DOI: 10.1016/j.neuroimage.2012.12.031

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/1eptrw-_e7s/130228171357.htm

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Friday, March 1, 2013

Fusion as an energy source? Physicists demonstrate the acceleration of electrons by a laser in a vacuum

Feb. 27, 2013 ? Accelerating a free electron with a laser has been a longtime goal of solid-state physicists. David Cline, a distinguished professor in the UCLA Department of Physics and Astronomy, and Xiaoping Ding, an assistant researcher at UCLA, have conducted research at Brookhaven National Laboratory in New York and have established that an electron beam can be accelerated by a laser in free space.

This has never been done before at high energies and represents a significant breakthrough, Cline said, adding that it also may have implications for fusion as a new energy source.

In free space, a plane-wave laser is unable to accelerate an electron, according to the Lawson-Woodward theorem, posited in 1979. However, Yu-kun Ho, a professor at China's Fudan University in Shanghai, and his research group have proposed a concept of what physicists refer to as the capture-acceleration scenario to show that an electron can be accelerated by a tightly focused laser in a vacuum.

In the capture-acceleration scenario, the diffraction from a tightly focused laser changes not only the intensity distribution of the laser but also its phase distribution, which results in the field phase velocity being lower than the speed of light in a vacuum in some areas.

Thus, a channel that overlaps features of both strong longitudinal electric field and low-laser-phase velocity is created, and electrons can receive energy gain from the laser. The acceleration effect increases along with increasing laser intensity, Cline said. This channel for electrons may be useful for other scientific endeavors, such as guiding an electron beam into a specific region of laser fusion applications, he said.

A possible application of this discovery is the use of laser plasma fusion to provide a new energy source for the U.S. and other countries. The focus of the laser generates a natural channel that can capture electrons and drive them into a pellet that explodes, by fusion, to produce excess energy, Cline said.

With federal funding from the U.S. Department of Energy, a project to carry out a proof-of-principle beam test for the novel vacuum acceleration at Brookhaven National Laboratory's Accelerator Test Facility (BNL-ATF) has been proposed and approved -- a collaboration among the UCLA Center for Advanced Accelerators, of which Cline is principal investigator, Ho's group and the Accelerator Test Facility team.

BNL-ATF is one of the few facilities that can provide both a high-quality electron beam and a high-intensity laser beam for the beam test, Cline said. Ho's group provides theoretical support. UCLA scientists -- Cline, Ding and Lei Shao, a former UCLA physics graduate student of Cline's -- are responsible for the whole experiment and the experimental data analysis.

Simulation research work and hardware design have been done in accordance with BNL-ATF's experimental conditions. The simulation results predict that vacuum laser acceleration phenomena can be observed with ATF's diagnostic system.

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The above story is reprinted from materials provided by University of California - Los Angeles.

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Journal References:

  1. L. Shao, D. Cline, X. Ding, Y.K. Ho, Q. Kong, J.J. Xu, I. Pogorelsky, V. Yakimenko, K. Kusche. Simulation prediction and experiment setup of vacuum laser acceleration at Brookhaven National Lab-Accelerator Test Facility. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2013; 701: 25 DOI: 10.1016/j.nima.2012.09.053
  2. David Cline, Lei Shao, Xiaoping Ding, Yukun Ho, Qing Kong, Pingxiao Wang. First Observation of Acceleration of Electrons by a Laser in a Vacuum. Journal of Modern Physics, 2013; 04 (01): 1 DOI: 10.4236/jmp.2013.41001

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Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/oRWFsnC7UMg/130228093833.htm

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Video: 'League of Legends' hits the Mac

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Source: http://www.nbcnews.com/video/in-game/51009505/

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South Dakota extends abortion wait period for weekends, holidays

(Reuters) - The South Dakota Senate on Thursday passed a bill affecting abortion waiting times that could potentially make them the longest in the country.

The bill, passed by a 24-9 vote in the Republican-controlled Senate, would exclude weekends and holidays from the calculation of a 72-hour waiting period for an abortion.

The bill was passed by the state House last week. It will go to Governor Dennis Daugaard, a Republican, next week, his spokesman, Tony Venhuizen, said.

Venhuizen said he could not say if the governor would sign the bill. He said Daugaard has been supportive of the "concept" of the longer waiting period and had supported the 72-hour waiting period previously put into law.

If it becomes law, the bill could potentially extend a waiting period to six days if a woman requested an abortion just before a three-day weekend. Utah also has a 72-hour waiting period.

"This bill has absolutely nothing to do with helping women," said Sarah Stoesz, chief executive of Planned Parenthood Minnesota, North Dakota, South Dakota. "Instead, this bill is about further delaying women from having an abortion and protecting the convenience and schedules of crisis pregnancy centers - a stunningly cynical use of the legislature and of taxpayer dollars."

Venhuizen said the measure addresses a practical consideration. "The rationale behind the waiting period is that it would allow time for counseling, and counseling is available through business hours," he said.

Planned Parenthood had challenged South Dakota's 72-hour waiting period, but withdrew the challenge late last year, removing a court hold on the implementation of the law. The 72-hour law will be enforced in the next several weeks, according to Planned Parenthood.

The South Dakota vote came on the same day that Arkansas joined seven other U.S. states on Thursday in banning most abortions after 20 weeks of pregnancy as the Republican-controlled state Senate voted to override a veto of the legislation by Democratic Governor Mike Beebe.

(Reporting By Mary Wisniewski; Editing by Leslie Adler)

Source: http://news.yahoo.com/south-dakota-extends-abortion-wait-period-weekends-holidays-234144511.html

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